Novel tetrapeptide matrikines. From in silico peptide discovery to formulation delivery

Following 15 years of research into skin ageing and repair, No7 this year unveiled a novel matrix-derived peptide blend created with scientists at the University of Manchester.  The No7 R&D team will take you on the journey from discovery to commercialisation; sharing the unique in silico approach taken to identify bioactive naturally-occurring peptides released from matrix degradation then test their efficacy using omics techniques, through to the approach taken to formulate these peptides into a lightweight product designed to optimise peptide penetration whilst being aesthetically pleasing for consumers.

 Key takeaways: In silico prediction of matrix degradation can be used to identify bioactive peptides. Considering delivery alongside aesthetics is essential when formulating effectively with peptides.