Microbiome and Quorum Sensing communication in skin health
Time: 4:00 pm - 4:30 pm
Date: 12 November
The human skin microbiome plays a key role in maintaining a healthy skin. This microbiome is made of complex microbial communities which live on the skin and which assemble into biofilms. Biofilms are ubiquitous and present not only in different areas of our bodies but also in the outside environment. At the National Biofilms Innovation Centre (NBIC), in partnership with industry, we are developing novel strategies to prevent, detect, manage and engineer biofilms. Microbes living in these biofilm communities communicate using small chemicals known as quorum sensing (QS) signals. These signals play an important role in the interaction between the microbiome and the host as well are being key switches for the production of toxic products by some microorganisms which can damage the host. We are designing strategies to interfere with QS signalling as a way to reduce or inhibit the damage caused by some microbes which will result in the regeneration of a healthy microbiome ultimately having a positive impact on the host including the maintenance of a healthy skin.