The collagen superfamily includes 28 members, divided into 8 categories. In the skin, collagens I and III are the most expressed and belong to the fibrillar collagens category. However, other collagens are expressed and play crucial roles in cell anchorage, matrix assembly, cell signaling and skin homeostasis. During aging, the biosynthesis of collagens is declining, associated with the appearance of wrinkles and loss of skin quality markers such as luminosity or firmness.
Given the importance of all collagens and their interconnection, a new active ingredient was designed by artificial intelligence (AI) to preserve the skin collagen ecosystem from aging. This active ingredient relies on a patented molecular complex sodium hyaluronate (HA), tripeptide-1 and hexapeptide-9, integrated into cellulose gum matrix.
The beneficial effects of this molecular complex, leveraging the biomimicry of skin collagens, were highlighted by an increased expression of 20 collagen chains in ex vivo and in vitro studies.
These results were supported by two double-blind clinical studies demonstrating short term and long-term skin benefits on both Caucasian and Asian volunteers. The first study showed an immediate improvement of skin hydration, glow and smoothness at 3 minutes and 4 hours after mask application. In the second study, less wrinkles were observed in the crow’s feet area compared to placebo associated with better skin hydration and elasticity after 1 month.
Additionally, the ingredient provides an instant sensory feel, comparable to silicone-like sensory, contributing to the velvet touch and smooth effect, and adding a unique texture experience.
In conclusion, the efficacy of this innovative technology was significantly demonstrated across collagens, suggesting anti-aging benefits, as confirmed by clinical data. By combining the power of biomimicry and AI, we demonstrated how science can meet consumer expectations.
